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Thursday, January 26, 2012

How to Control Estrogen Levels


So what can you do to slow down the endocrinological avalanche caused by estrogen?  It's simple:  read over my link on Estrogen Increasers and then consider these Estrogen Controllers as well:
1) Zinc. Zinc actually inhibits the aromatase enzyme. So, if you are zinc depleted, you may get a benefit from supplementation.  To find out more, read this link on Zinc and ZMA.
CAUTION:  Don't go crazy with zinc - if you take too much it causes more problems as it helps. For example, it can lead to copper depletion and some researchers believe it can contribute to dementia in overly high doses.  Also, researchers have found that there are two common food additives, propyl gallate (a preservative) and 4-hexylresocrinol (a discoloration preservative), that are xenoestrogens and can mimic estrogen. [11]  These kind of xenoestrogens have been linked to reduced sperm counts (and increased breast cancer in women).
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2) Lose Weight. The major contributor to an increase in aromatase is, you might have guessed it, that extra weight around your midsection. Fat cells are known for storing the aromatase enzyme and many studies have shown its ill effects on testosterone. Is it any wonder?  Those extra pounds actually slowly biochemically neuter the middle aged and beyond male. Even worse, fat cells lead to the creation of, actually conversion to more estrogen which displaces testosterone throughout the body. How many of us have seen overweight males with "man boobs" that are the result of just this phenomenon?  And those love handles on the side of your gut: they should really be called loveless handles. One study looked at 64 severely obese men and their average testosterone was 340 even though the average age was only 48! [7] Furthermore, the authors found that weight was associated with an increase in estrogen and a decrease in testosterone. They then looked at these men when given a certain kind of bypass surgery that lowered their weight and BMI.  You guessed it:  estrogen decreased and testosterone increased significantly! By the way, fat cells are also known for spitting out chemicals that cause inflammation throughout your body leading to damaged heart and erectile tissues. Being overweight is strongly correlated to erectile issues for this and several other reasons. (I discuss the many problems of being overweight here.) So if you won't drop the pounds for the wife or your health, at least do it for the Little Gipper. 
3) BANNED: 6-OXO.  This supplement appears to be the "real deal", a legitimate estrogen blocker. Estrogen is a huge issue for aging males for many reasons, but one of the nastiest is that increasing estrogen actually decreases testosterone.  (See this link on How to Limit Estrogen for more information.) Some estrogen is important for brain and bone health but that is not an issue for most aging males.  Many 55 year olds have close to or more estrogen than their wives!  In 2007 6-OXO was studied definitely and the results look excellent:  resistance-trained males saw "FT [free testosterone] and DHT underwent overall increases of 90% and 192% for 300 mg 6-OXO and 84% and 265% for 600 mg, respectively, while T/E increased 53% and 67% for 300 mg and 600 mg 6-OXO, respectively". [7]  Notice the substantial boosts in free testosterone and the testosterone to estrogen ratio.  In fact, 6-OXO was so good that the FDA, in its nearly infinite wisdom of course, decided to ban this supplement in August of 2009. [13] This goes back to what I always say, "If it's a legitimate testosterone booster, the FDA will ban it".  And it's not all bad:  6-OXO undoubtedly needed more clinical history.  For example, the above study [7] also showed substantial increases in DHT and estrone for example.  
When does low testosterone cause erectile dysfunction or harden your arteries? 300 ng/dl? 400? Find out what the studies say in Low Testosterone By The Numbers.
4) Broccoli. Broccoli (and other cruciferous vegetables such as cauliflower and cabbage) are powerful estradiol blockers. This is done by special phytochemicals in broccoli called indoles, the most powerful being indole-3-carbinol (I3C).  I3C is quite powerful and has been studied extensively for its estradiol-lowering effects in women in the hopes of breast cancer prevention.  But guys can achieve the same effect and that is undoubtedly one of the reasons that broccoli consumption is associated with Prostate Cancer Protection NOTE: Broccoli is easy to fix:  just put raw florets in a coffee cup with a half inch of water on the bottom and heat for around two minutes in a microwave.  The steam for the bottom of the cup will cook the broccoli soft and tender.  Then just add a little salt and it is ready to eat.
5) Grape Seed Extract.  Many studies have shown Grape Seed Extact to be a good aromatase inhibitor [10].  It also, in vitro at least, gives Vitamin C a longer shelf life.  However, Grape Seed Extract has a couple of cautions that need to go along with it:  1) in combination with Vitamin C it apparently raises blood pressure [9] and 2) it may slightly decrease free testosterone because it can raise SHBG, the protein that binds to testosterone. 
6) Chrysin.  Chrysin has had meager results in some studies. [3] However, Life Extension Foundation seem to have overcome these underlying issues by including piperine in their formulation for greater absorbability. See my Review on Super Miraforte for more information.  CAUTION:  Supermiraforte has been around quite awhile.  However, it should be noted that one study showed Chrysin inhibiting the conversion of T4 to T3 and thus negatively impacting thyroid function. [4] This could potentially lead to weight gain, which would sabotage estrogen control.
Again, I encourage you to also look over my link on Estrogen Increasers to avoid those things that can negatively boost estrogen levels in our everyday life.
My 5 Top Erectile Supplements w/ solid research.
REFERENCES:
1) Agents Actions, Jun 1987,21(1-2):223-8
2) Medical Hypotheses, Jun 2001, 56(6):702-708
3) J Steroid Biochem Mol Biol,Sep 2001,78(3):231-9Biol,Sep 2001,78(3):231-9
4) Prog Clin Biol Res, 1986, 213:359-71, "Iodothyronine deiodinase is inhibited by plant flavonoids"
5) J Int Soc Sports Nutr,Oct 19 2007,4:13
6) Med and Sci in Sports & Exerc,1999, 31:483
7) Journal of Clinical Endocrinology & Metabolism, published online on January 27, 2009, Submitted on July 24, 2008, Accepted on January 15, 2009, "Effect of Roux-en-Y Gastric Bypass Surgery on the Sex Steroids and Quality of Life in Obese Men", Ahmad Hammoud MD, MPH*, et. al.
8) Cancer Res, Jun 1 2006, 66:5960-5967
9) J Hypertensm 2005 Feb, 23(2):427-34
10) Cancer Res. 2006 Jun 1;66(11):5960-7
11)  Alessio Amadasi et al., "Identification of Xenoestrogens in Food Additives by an Integrated in Silico and in Vitro Approach, Chemical Research in Toxicology", 2009; 22(1):52
12) J Clin Endocrin Metab, 1993, 77: 375-381, "Effect of aging on endogenous levels of 5-alpha-dihydrotestosterone, testosterone, estradiol and estrone in epithelium and stroma of normal and hyperplastic human prostate"
13) http://www.fda.gov/NewsEvents/Newsroom/ PressAnnouncements/ucm152358.htm
14) http://www.prnewswire.com/news-releases/consumer- reports-tests-find-wide-range- of-bisphenol-a-in-canned-soups-juice-and-more-68723862.html



http://www.peaktestosterone.com/Estrogen_Controlling.aspx

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